Leveraging Vaccines to Reduce Antibiotics Use and Prevent Antimicrobial Resistance
Chair(s):
Marc Mendelson
,
Marc Mendelson
Affiliations:
Afreenish Amir
Afreenish Amir
Affiliations:
Speaker(s):
Anthony Fiore
,
Anthony Fiore
Affiliations:
Paul Tambyah
Paul Tambyah
Affiliations:
IKEEP. Faculty / Presenter(s) . 09/15/21; 337254
Marc Mendelson
Afreenish Amir
Anthony Fiore
Paul Tambyah
About this activity
References
ISID “Leveraging Vaccines to Reduce Antibiotics Use and Prevent Antimicrobial Resistance” Webinar
This webinar was hosted on Sep 15, 2021, Wednesday 9:00 am – 10:00 am EDT

Moderators:
Marc Mendelson
Afreenish Amir

Speakers:
Anthony Fiore
Paul Tambyah

Antimicrobial resistance (AMR) is one of the biggest global health threats. Antibiotics are becoming increasingly ineffective as drug-resistance spreads leading to more difficult to treat infections. Fighting this threat is a public health priority that requires a collaborative global approach across sectors.


Controlling AMR demands improvements in infection prevention, antimicrobial stewardship, and antimicrobial discovery. A powerful measure to reduce the use of antimicrobials, and hence development of resistance, is to prevent the occurrence of infections. Vaccines can impact AMR in two ways. Vaccines can reduce or eliminate the risk of infection due to antibiotic-resistant strains, for example pneumococcal vaccine. Vaccines can also have a secondary effect on AMR by preventing antibiotic use by reducing the rates of viral febrile illness episodes and the likelihood of secondary bacterial infections following the prevented episode. Viral infections are a strong driver of use and misuse of antibiotics and vaccines are an impactful and effective public health measure for the prevention of many viral infections. Single or combination vaccines may ultimately result in synergistic effects on decreasing antimicrobial use and therefore resistance. In this way, vaccines targeting viral illnesses become a tool to reinforce policies of antibiotic stewardship.

WHO has developed a strategy to articulate the role of vaccines against AMR and an action framework that describes a vision for vaccines to contribute fully, sustainably and equitably to the prevention and control of antimicrobial resistance by preventing infections and reducing antimicrobial use. During this webinar, speakers will discuss how vaccines targeting viral illnesses contribute to the battle against AMR by preventing infections and by reducing antimicrobial use. 

Please take 2 min after the webinar to fill out our evaluation form: https://isid.typeform.com/to/vDqYDBPQ
 
  • Klugman KP, Black S. Impact of existing vaccines in reducing antibiotic resistance: Primary and secondary effects. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12896-12901. doi: 10.1073/pnas.1721095115. https://pubmed.ncbi.nlm.nih.gov/30559195/

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