Knowledge Exchange by ISID

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This webinar was hosted on May 18, 2021, 09:00 AM - 10:00 AM EST, and will be available for On-Demand access with slide navigation. 

If you are unable to attend the live event, an on-demand version will be available one hour after the webinar’s conclusion, and a post-produced version (with slide navigation) within 2 to 3 hours.





Chair: William Hope (UK),
Co-Chair: Sophie Yacoub (Vietnam)

Talaromyces Marneffei
Thuy Le, (Vietnam, US)

Cryptococcus Neoformans
Henry Mwandumba, (Malawi)

The aim of implementing an antifungal stewardship program is to optimize the use of antifungal drugs to achieve the best outcomes while minimizing adverse events and the emergence of resistance. Antifungal stewardship is less established than antibacterial stewardship because of a narrower and more complex evidence base along with fewer available drugs. Moreover, the diagnosis of fungal infections can be complex with an urgent need for reliable noninvasive and rapid diagnostic tests that can be used across different resource levels. 
 
During this session, experts will provide updates on the diagnosis, treatment, monitoring and prevention strategies for Cryptococcus neoformans and Talaromyces marneffei (formerly Penicillium marneffei), both important opportunistic pathogens in patients with AIDS and other immunosuppressive conditions. Focus will be on diagnostic options and treatment and prevention strategies in areas with highest burden of disease, from Southeast Asia to southern China and sub-Saharan Africa. 
 
Experts will discuss how antifungal stewardship programs can take a multi-pronged approach to ensure timely testing and suitable prescribing and how institutional guidelines can guide diagnostic testing in at-risk populations; appropriate choice, dose, and duration of antifungal agents; therapeutic drug monitoring; and opportunities for de-escalation and intravenous-to-oral conversion for these pathogens.

This webinar is supported by an unrestricted educational grant from bioMérieux.

Please take 2 minutes after the webinar to answer our evaluation form by clicking on the link: https://isid.typeform.com/to/MHmw5vvc
The aim of implementing an antifungal stewardship program is to optimize the use of antifungal drugs to achieve the best outcomes while minimizing adverse events and the emergence of resistance. Antifungal stewardship is less established than antibacterial stewardship because of a narrower and more complex evidence base along with fewer available drugs. Moreover, the diagnosis of fungal infections can be complex with an urgent need for reliable noninvasive and rapid diagnostic tests that can be used across different resource levels. 

During this session, experts will provide updates on the diagnosis, treatment, monitoring and prevention strategies for Cryptococcus neoformans and Talaromyces marneffei (formerly Penicillium marneffei), both important opportunistic pathogens in patients with AIDS and other immunosuppressive conditions. Focus will be on diagnostic options and treatment and prevention strategies in areas with highest burden of disease, from Southeast Asia to southern China and sub-Saharan Africa. 

Experts will discuss how antifungal stewardship programs can take a multi-pronged approach to ensure timely testing and suitable prescribing and how institutional guidelines can guide diagnostic testing in at-risk populations; appropriate choice, dose, and duration of antifungal agents; therapeutic drug monitoring; and opportunities for de-escalation and intravenous-to-oral conversion for these pathogens.

 
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